When Meg Ryan and Dennis Quaid ended their 10-year marriage in 2001 in the wake of rumours she had an affair with “Proof of Life” co-star Russell Crowe, the nasty split played out publicly as the two ex-spouses took shots at each other in the press.

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Nearly two decades later, Quaid is opening up about his failed marriage to the “When Harry Met Sally” star, now admitting that the relationship became strained when her fame began to eclipse his.

In a clip from an interview set to air on Monday’s edition of “Megyn Kelly Today”, obtained by the Daily Mail, the star of such films as “The Right Stuff” and “Innerspace” (in which he co-starred with Ryan) reveals that his ego took a big hit when she became “America’s Sweetheart” while his own career stalled.

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“When we met, you know, I was the big deal and then my career [came to a halt],” Quaid tells Kelly in the clip, imitating the sound of a car’s screeching brakes.

“And I have to admit it, I actually did feel like I disappeared,” adds Quaid, 64. “I didn’t think I was that small… but I was.”

The success of “Sleepless in Seattle” catapulted Ryan to a whole new level of celebrity, and Quaid recalls how things changed, seemingly overnight, remembering walking in public together while fans screamed, “Meg! Meg!” while ignoring him entirely.

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However, he admits “it really was a growth opportunity. I learned from that.”

In fact, despite their rancorous split, the thrice-wed Quaid now looks back on his marriage to Ryan as “my most successful relationship in my life.”

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Elsewhere in the interview, Quaid talks about his battle with drug addiction and how he could have easily died if he didn’t seek help. “I was basically doing cocaine pretty much on a daily basis during the 80s,” he admits.

“I spent many, many a night screaming at God to please take this away from me, I’ll never do it again because I’ve only got an hour before I have to be at work.”

It wasn’t until a “white light experience” that he realized he needed serious help before he lost everything. “I had one of those white light experiences that night where I kind of realized I was going to be dead in five years if I didn’t change my ways. The next day I was in rehab.”