Kathy Griffin paid a visit to Global‘s “The Late Show with Stephen Colbert” on Friday, and got candid about the fallout from that notorious 2017 photo in which she proudly posed with the fake decapitated head of President Donald Trump.

As Griffin, 58, told Colbert, what some people wrote off as a questionable joke landed her in some serious “real-life trouble” when she found herself facing charges of conspiracy to assassinate the president of the United States, revealing that the whole thing “changed my life irrevocably.”

According to Griffin, when she subsequently embarked on an 18-country comedy tour, she discovered she’d been placed on the U.S. government’s no-fly list, which meant she was “detained at every single airport” she visited.

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“So a lot of people thought, you know, I got a call from the Secret Service or got in fake Hollywood trouble. But, no, this is real-life trouble,” Griffin explained. “That’s where your tax dollars went, everybody, investigating Kathy Griffin.”

Admitting that her career still hasn’t recovered, Griffin also said that she lost “75 per cent” of her friends, “that never came back,” telling Colbert, “The walls caved in on me.”

In hindsight, she told Colbert she would probably not “do that particular thing again,” but revealed that her experience placed her on “a comedy mission” to defend other female comedians — including Samantha Bee and Michelle Wolf — who have faced backlash from conservatives after making controversial jokes about Trump and his family.

RELATED: Kathy Griffin Takes Back Trump Apology For Severed Head Controversy: ‘F**k Him!’

Meanwhile, here’s what Griffin had to say about Kevin Hart stepping down from hosting the Academy Awards in an interview with ET Canada:

“The Late Show with Stephen Colbert” airs weeknights at 11:35 p.m. ET/PT on Global; you can also watch full episodes online.