The biggest “Riverdale” romance is over.

Co-stars and real-life couple Lili Reinhart and Cole Sprouse have split after dating for almost three years, Page Six reported.

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A source told the outlet that the couple broke up relatively recently, and have been quarantining separately during the pandemic.

Another insider told People, that the on-and-off couple are currently “off.”

Skeet Ulrich’s girlfriend Megan Blake Irwin recently hinted during an Instagram Live session that Reinhart and Sprouse had split up.

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“Do you think that Cole Sprouse and Lili Reinhart are a cute couple?” a fan asked.

“I think they were a very cute couple,” Ulrich responded; Irwin added, “They were a very cute couple,” stressing the word “were.”

“They’re both beautiful people,” she said.

According to a E!News source, their breakup might not be for good.

“Lili and Cole were in a good place when ‘Riverdale’ was shut down due to the coronavirus outbreak, but they isolated separately and distance has never been a good thing for their relationship,” an insider shared. “When Cole and Lili are around each other often, things are very good. Their relationship is very intimate and affectionate, but things become much more complicated when they’re apart.”

Another source added, “Distance is never good for their relationship. They decided not to quarantine together and knew off the bat that it wasn’t going to work. They both know their communication is better when they are together in person, and it just wasn’t working.”

“They know they will likely reconcile once filming resumes,” the insider added. “Both aren’t interested in dating other people, just using this time to chill and focus on themselves.”

The publication added that the couple has been apart for about a month.

ET Canada has reached out to both Sprouse and Reinhart’s reps for comment.