Happy birthday, Kelly Ripa!

On Friday, October 2, the talk show host rang in the big 5-0 and received several well-wishes from her family and celebrity friends.

Ripa was welcomed with extravagant balloon arrangements on “Live with Kelly and Ryan” before Seacrest delivered a very special message: “Happy Birthday to our leader, our trailblazer, our partner, my co-host, my family member, my friend. It’s wonderful to sit next to you every single day. I’m so proud to be your friend and partner on television and I love you so much.”

RELATED: Kelly Ripa Gushes Over Husband Mark Consuelos’ ‘Superpower’ As She Marks Her 50th Birthday

The host even received a video message from Oprah, who jokingly urged her not to do a nude photoshoot after she was inspired by Gwyneth Paltrow’s viral post on her 48th birthday.

“By the way, spare Lola — there is no need to go posting in your birthday suit on Instagram,” said Oprah.

View this post on Instagram

Conversations with my daughter ♥️🎁🎈🎉

A post shared by Kelly Ripa (@kellyripa) on

Later in the show, Ripa’s husband Mark Consuelos called in from Vancouver to surprise her with a stunning bouquet of flowers, hand-delivered by her son Michael.

Meanwhile, Consuelos also took to Instagram to celebrate his “little ray of sunshine.”

Andy Cohen also gave his well-wishes, posting a series of photos of himself and Ripa through the years: